Job Description
Senior Scientist – Bioproduction & Bioprocessing
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📍 Rockville, MD | On-site
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🧬 Cell Line Development | Protein Production | CHO / HEK | Bioprocessing
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I’m partnering with an established life science technology company that is expanding its R&D team and looking for a Senior Scientist with strong upstream mammalian cell culture and protein production experience.
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This is a hands-on R&D position focused on building and developing in-house bioproduction capabilities. You’ll work on both stable and transient protein production workflows, helping translate new approaches into robust, reproducible processes that can ultimately support customers and field teams.
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What you’ll be working on:
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- Developing stable pools and cell line development workflows, particularly using CHO and other mammalian cell systems.
- Building and optimising transient protein and antibody production workflows.
- Evaluating different media, feeds, culture conditions and expression approaches.
- Supporting the development of workflows for complex and difficult-to-express antibodies/proteins.
- Exploring approaches including random integration and transposon-based cell line development.
- Creating clear SOPs and transferring scientific workflows internally to Field Applications and other customer-facing teams.
- Working closely with R&D, Engineering, Product Management and commercial teams.
- Attending scientific conferences to stay close to new developments in bioproduction and present internal research.
- Occasionally supporting field teams and customer demonstrations with deeper bioprocessing expertise.
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What we’re looking for:
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- Strong hands-on experience in upstream mammalian cell culture and protein production.
- Experience with CHO and/or HEK cells.
- Practical experience developing stable cell lines/stable pools.
- Experience with transient expression and recombinant protein or antibody production.
- An understanding of upstream process optimisation, including media/feed strategies and culture conditions.
- Strong scientific communication skills — someone who can explain not only what they did, but why.
- A collaborative, approachable personality suited to a closely integrated R&D environment.
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This could also suit someone coming from a strong academic, NIH or research institute background who wants to transition into industry, provided they have directly relevant cell line development and protein production experience.
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This is not primarily a downstream purification role — the key experience is upstream cell line development, expression and protein production.
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The company offers a strong scientific culture, annual bonus and equity alongside its wider benefits package, with good opportunity to grow as the R&D team continues to develop.
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📩 If you have experience across mammalian cell line development and bioproduction and would like to hear more, apply or message me directly.
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